Vicki Losick
Assistant Professor
Vicki Losick
Ph.D.
Contact
Higgins Hall 501
Telephone: 617-552-6432
Email: vicki.losick@bc.edu
ORCID 0000-0003-4608-2980
Education
- Ph.D., Tufts University School of Graduate Biomedical Sciences
Department
Publications
Grendler J, Lowgren S, Mills M, and Losick VP. Wound-induced polyploidization is driven by Myc and supports tissue repair in the presence of DNA damage. Development. 2019, Aug 2; pii: dev173005.
Gjelsvik KJ, Besen-McNally R, and Losick VP. Solving the polyploid mystery in health and disease. Trends in Genetics. 2019, Jan;35(1):6-14.
Published Losick VP. Wound-induced polyploidy is required for tissue repair. Adv Wound Care (New Rochelle). 2016, Jun 1;5(6):271-278.
Losick, VP, Jun, AS, and Spradling, AC. Wound-induced polyploidization: regulation by Hippo and JNK signaling and conservation in mammals. PLoS One. 2016 Mar 9;11(3):e0151251.
Losick, VP, Fox DT, and Spradling, AC. Polyploidization and cell fusion contribute to wound healing in the adult Drosophila epithelium. Current Biology. 2013, Nov 18; 23(22):2224-32.
Liu M, Uehara T, Losick VP, Park JT, and Isberg RR. A Legionella pneumophila protein that facilitates evasion from Nod1 recognition. Cell Host Microbe. 2012, Aug 16; 12(2):166-76.
Losick VP, Morris LX, Fox DT, Spradling A. Drosophila stem cell niches: a decade of discovery suggest a unified view of stem cell regulation. Developmental Cell. 2011, Jul 19; 21(1):159-71.
Losick VP, Haenssler E, Moy M, and Isberg RR. LnaB: a Legionella pneumophila activator of NF-kappaB. Cell Microbiology. 2010, Aug; 12(8):1083-97.
Li Z, Dugan AS, Bloomfield G, Skelton J, Ivens A, Losick VP, and Isberg RR. The amoebal MAP kinase response to Legionella pneumophila is regulated by DupA. Cell Host Microbe. 2009, Sep 17; 6(3):253-67.
Losick VP* , Stephan KS* , Isberg, RR, Poltorak A. A hemidominant Naip5 allele in MOLF/Ei-derived macrophages restricts L. pneumophila intracellular growth. Infection and Immunity. 2009, Jan; 77(1):196-204.
*Co-primary authors. Losick VP and Isberg RR. NF-kappaB translocation prevents host cell death after lowdose challenge by Legionella pneumophila. Journal of Experimental Medicine. 2006, Sep 4; 203(9):2177-89.
Losick VP, Schlax PE, Emmons RA, Lawson TG. Signals in Hepatitis A Virus P3 region Proteins recognized by the ubiquitin-mediated proteolytic system. Virology. 2003, May 10; 309(2):306-19.