Research Scientists
Sudarshan Bhattacharjee
Senior Research Associate
Sudarshan Bhattacharjee
Ph.D.
Contact
Altindis Lab - Higgins 520
Telephone: 617-552-2841
Email: sudarshan.bhattacharjee@bc.edu
ORCID 0000-0002-3607-9967
Education
- Ph.D. in Biochemistry, Calcutta University, India
- M.Sc. in Microbiology, Calcutta University, India
- B.Sc. in Microbiology, Calcutta University, India
Research Interests
IGF1 signaling in Breast Cancer, Virus Insulin/IGF1 Like
Peptides as IGF-1R antagonists, Tumor Microenvironment and Metabolism, Obesity
associated Insulin Resistance, Breast Cancer Pre-Clinical Models.
Department
Selected Publications
- Bhattacharjee, Sudarshan, Nabanita Das, Ashok Mandala, Satinath Mukhopadhyay, and Sib Sankar Roy. "Fenofibrate Reverses Palmitate Induced Impairment in Glucose Uptake in Skeletal Muscle Cells by Preventing Cytosolic Ceramide Accumulation." Cellular Physiology and Biochemistry 37, no. 4 (2015): 1315-28.
- Bhattacharjee, Sudarshan, Jianing Gao, Yao Wei Lu, Shahram Eisa-Beygi, Hao Wu, Kathryn Li, Amy E Birsner, et al. "Endothelial Foxm1 and Dab2 Promote Diabetic Wound Healing." JCI insight 10, no. 2 (2025): e186504.
- Bhattacharjee, Sudarshan, Yang Lee, Bo Zhu, Hao Wu, Yabing Chen, and Hong Chen. "Epsins in Vascular Development, Function and Disease." Cellular and Molecular Life Sciences 78, no. 3 (2021): 833-42.
- Das, Nabanita, Ashok Mandala, Sudarshan Bhattacharjee, Debasri Mukherjee, Debasish Bandyopadhyay, and Sib Sankar Roy. "Dietary Fat Proportionately Enhances Oxidative Stress and Glucose Intolerance Followed by Impaired Expression of the Genes Associated with Mitochondrial Biogenesis." Food & function 8, no. 4 (2017): 1577-86.
- Dong, Yunzhou, Yang Lee, Kui Cui, Ming He, Beibei Wang, Sudarshan Bhattacharjee, Bo Zhu, et al. "Epsin-Mediated Degradation of Ip3r1 Fuels Atherosclerosis." Nature communications 11, no. 1 (2020): 3984.
- Dong, Yunzhou, Beibei Wang, Kui Cui, Xiaofeng Cai, Sudarshan Bhattacharjee, Scott Wong, Douglas B Cowan, and Hong Chen. "Epsins Negatively Regulate Aortic Endothelial Cell Function by Augmenting Inflammatory Signaling." Cells 10, no. 8 (2021): 1918.
- Dong, Yunzhou, Beibei Wang, Mulong Du, Bo Zhu, Kui Cui, Kathryn Li, Ke Yuan, et al. "Targeting Epsins to Inhibit Fibroblast Growth Factor Signaling While Potentiating Transforming Growth Factor-Β Signaling Constrains Endothelial-to-Mesenchymal Transition in Atherosclerosis." Circulation 147, no. 8 (2023): 669-85.
- Duraisamy, Arul J, Manish Mishra, Sudarshan Bhattacharjee, and Renu A Kowluru. "Deciphering Ocular Diseases on an Epigenetic Platform." In Prognostic Epigenetics, 117-38: Academic Press, 2019.
- Ghosh, AK, E Mitra, N Das, M Dutta, S Bhattacharjee, A Chattopadhyay, SS Roy, and D Bandyopadhyay. "Protective Effect of Aqueous Bark Extract of Terminalia Arjuna against Copper-Ascorbate Induced Oxidative Stress in Vitro in Goat Liver." Journal of Cell & Tissue Research 13, no. 2 (2013).
- Mandala, Ashok, Nabanita Das, Sudarshan Bhattacharjee, Bidisha Mukherjee, Satinath Mukhopadhyay, and Sib Sankar Roy. "Thioredoxin Interacting Protein Mediates Lipid-Induced Impairment of Glucose Uptake in Skeletal Muscle." Biochemical and Biophysical Research Communications 479, no. 4 (2016): 933-39.
- Mishra, Manish, Arul J Duraisamy, Sudarshan Bhattacharjee, and Renu A Kowluru. "Adaptor Protein P66shc: A Link between Cytosolic and Mitochondrial Dysfunction in the Development of Diabetic Retinopathy." Antioxidants & redox signaling 30, no. 13 (2019): 1621-34.
- Singh, Bandana, Kui Cui, Qianman Peng, Kathryn Li, Bo Zhu, Sudarshan Bhattacharjee, Daniel Osorio, et al. "Novel Role of Endothelial Cd47 in the Regulation of Pathogenesis of Atherosclerosis." Arteriosclerosis, Thrombosis, and Vascular Biology 43, no. Suppl_1 (2023): A338-A38.
- Song, Kai, Xiaofeng Cai, Yunzhou Dong, Hao Wu, Yong Wei, Uma T Shankavaram, Kui Cui, et al. "Epsins 1 and 2 Promote Nemo Linear Ubiquitination Via Lubac to Drive Breast Cancer Development." The Journal of Clinical Investigation 131, no. 1 (2021).
- Wu, Hao, Vikram Norton, Kui Cui, Bo Zhu, Sudarshan Bhattacharjee, Yao Wei Lu, Beibei Wang, et al. "Diabetes and Its Cardiovascular Complications: Comprehensive Network and Systematic Analyses." Frontiers in Cardiovascular Medicine 9 (2022): 841928.