Protein L-Isoaspartyl, D-Aspartyl O-Methyltransferases:

Catalysts for Protein Repair

From Protein Methyltransferases, Vol. 24, The Enzymes (Eds. F. Tamanoi and S. G. Clarke), pp. 383-431.

Clare O’Connor, Associate Professor and Associate Chair, Biology Department

Clare O’Connor’s recent review article, Protein L-Isoaspartyl, D-Aspartyl O-Methyltransferases: Catalysts for Protein Repair, provides an overview of research on this ancient and widely-distributed class of enzymes.  Thought to have an important role in protein repair, these enzymes may be critical players in the aging process.  In the video interview, Professor O’Connor also talks about her own work, her path to the sciences, and the changing picture of women in the sciences. 

Elsevier has granted permission for open access publication of this article, which first appeared in the long-established series, The Enzymes, Vol. XXIV.  An online version now resides in the institutional repository, eScholarship@BC, where it is accessible to a much wider audience than previously.

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Brief Excerpt (5:05 min)
Full Interview (18:54 min)

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Boston College Libraries Resources

The Drosophila Protein Isoaspartyl Methyltransferase with S-Adenosyl-L-Homocysteine.
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Selected Boston College databases for this area of research:

PubMed
Biosis Preview

Selected Boston College resources on women in science:

Chronicle of Higher Education
Web of Science

For further information about research in this area, contact Enid Karr, Bibliographer for Biology.