Masayuki Wasa

Masayuki Wasa

Assistant Professor of Chemistry
Ph.D., The Scripps Research Institute, 2013
JSPS Postdoctoral Fellow, Harvard University, 2013-2015

Selected Honors and Awards:
Japan Society for the Promotion of Science Postdoctoral Fellowship for Research Abroad, (2013-2015), Harvard University

Bristol-Myers Squibb Graduate Fellowship in Synthetic Organic Chemistry, (2009-2010), The Scripps Research Institute

Group Research Website

wasa@bc.edu    617-552-4311


Our research program is centered on the development of polyfunctional Lewis pair catalysis for practical synthetic transformations with applications in drug discovery and development, and alternative energy. We will utilize these Lewis pair catalysts to enable reactions of inert substrates that cannot be activated efficiently by catalysts with a single activation center. Specifically, our initial efforts are focused on systematic identification of catalysts that will allow: a) transition metal-free asymmetric hydrogenation of various unsaturated substrates, b) reduction of CO2 to methanol, c) transition metal-catalyzed oxidative coupling of CO2 and olefins, and d) late-stage regioselective functionalization of C–H bonds in biopotent molecules.

Representative Key Publications:

Wasa, M.; Liu, R. Y.; Roche, S. P.; Jacobsen, E. N. Asymmetric Mannich Synthesis of α-Amino Esters by Anion-Binding Catalysis. J. Am. Chem. Soc. 2014, 136, 12872.

Wasa, M.; Chan, K. S. L.; Zhang, X.-G.; Miura, M.; Yu, J. -Q. Ligand-Enabled Methylene C(sp3)–H Bond Activation with a Pd(II) Catalyst. J. Am. Chem. Soc. 2012, 134, 18570.

Wasa, M.; Engle, K. M.; Lin, D.; Yoo, E. J.; Yu, J. -Q. Pd(II)-Catalyzed Enantioselective C–H Activation of Cyclopropanes. J. Am. Chem. Soc. 2011, 133, 19598.

Wasa, M.; Engle, K. M.; Yu, J. -Q. Pd(II)-Catalyzed Olefination of sp3 C-H Bonds. J. Am. Chem. Soc. 2010, 132, 3680.

Wasa, M.; Engle, K. M.; Yu, J. -Q. Pd(0)/PR3-Catalyzed Intermolecular Arylation of sp3 C-H Bonds. J. Am. Chem. Soc. 2009, 131, 9886.

Boston College Chemistry
  • Facebook
  • LinkedIn
  • Twitter
Boston College

Boston College Department of Chemistry

Merkert Center, Boston College, 2609 Beacon Street, Chestnut Hill, MA 02467-3860
© 2016 Boston College Chemistry