Cell and Developmental Biology
Our department explores a range of areas within cell and developmental biology. Please see below for details.
Molecular biology; Chromatin assembly and histone modifications in mammalian cells and fission yeast
Cytokinesis, polarization of the cytoskeleton
Cellular Organization. Mechanisms of nuclear movement and the role of nuclear movement in muscle development and disease pathogenesis.
Marc-Jan Gubbels, Ph.D.
Host cell invasion is at the heart of apicomplexan parasite pathogenesis. We use Toxoplasma gondii as a genetically tractable model to dissect this process. In addition we are analyzing the internal budding of daughter parasites during T. gondii cell division. Identification of key players in processes unique to the biology of Apicomplexa (invasion and division) is the first step towards development of more effective therapeutic options.
Structural analysis of amyloids and myelin sheaths
Laura Anne Lowery
Cytoskeletal dynamics during cell migration, axon outgrowth, development of the nervous system
Gene-environmental interactions in epilepsy and brain cancer
Central nervous system macrophages, neuroAIDS, AIDS pathogenesis, monocyte/macrophage biology