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Early-Stage Gene Transcription Creates Access to DNA

HoffmanProf. Charles Hoffman and an international team of researchers, probing how a yeast cell senses its cellular environment and makes decisions about whether or not to express a gene, found the process of transcribing non-coding RNAs is required for the eventual production of the protein-encoding RNA. The transient synthesis of these non-coding RNAs serves to unfurl the tightly wound DNA, essentially loosening the structure to allow for gene expression, they report in the September 2008 edition of the journal NatureBC News Release | Genetic Engineering News | Science Daily | ScienceCentric | Biology News Net | PhysOrg